Nick starts off the episode by talking about what a universal camera design is and why it might be nice to have (5:15). From there they talk about existing cameras that can be considered universal and how different qualities are more flexible than others. Nick describes the Mercury Camera System, a system that was designed from the start to be a universal design (22:40). Graham puts forward the concept that the APS film format should be considered a universal film format while name-dropping Mike Gutterman (28:30).
They move on to talking about the features of a universal camera (35:15) and what is most important about it. After that, they talk about how to approach a design of a universal camera (47:39).